1.
Indian J Exp Biol
;
2008 Feb; 46(2): 120-7
Article
in English
| IMSEAR
| ID: sea-62223
ABSTRACT
Four plants having known medicinal properties were screened for inhibition of goatpox virus (GTPV) replication in vitro. Of the 4 plants, extract of Acacia arabica (Babul) and Eugenia jambolana (Jamun) leaves had inhibition (%) 99.70 and 99.92 at their maximum non toxic concentrations, 99.93 +/- 0.38 and 1999.73 +/- 0.50 microg/ml, respectively in all cytopathic effect (CPE) inhibition assays. Inhibition of GTPV virus replication was further confirmed by PCR and SYBR Green based quantitative real-time QPCR assays specific for GTPV. Results indicated that the extract of Acacia arabica and Eugenia jambolana leaves inhibited GTPV replication in vitro.
Subject(s)
Acacia , Animals , Antiviral Agents/isolation & purification , Capripoxvirus/drug effects , Chlorocebus aethiops , Cytopathogenic Effect, Viral/drug effects , Eugenia , Plant Extracts/pharmacology , Plant Leaves , Poxviridae Infections/drug therapy , Vero Cells , Virus Replication/drug effects
2.
Article
in English
| IMSEAR
| ID: sea-118440